lBiopsy is the removal of tissue for the purpose of diagnostic examination (histopathological examination) .
Indications of Biopsy
lAny lesion that persists for more than 2 weeks with no apparent etiology
lAny inflammatory lesion that does not respond to local treatment after 10 to 14 days.
lPersistent hyperkeratotic changes in surface tissues.
lAny persistent tumescence, either visible or palpable beneath relatively normal tissue.
lInflammatory changes of unknown cause that persist for long periods
lLesion that interfere with local function
lBone lesions not specifically identified by clinical and radiographic findings
lAny lesion that has the characteristics of malignancy.
Types of Biopsy
lOral cytology
lAspiration biopsy
lIncisional biopsy
lExcisional biopsy
Cytology biopsy
- l as a diagnostic screening procedure to monitor large tissue areas for dysplastic changes.
- lfrequently used to screen for uterine cervix malignancy
- lMay be helpful with monitoring postradiation changes, herpes, pemphigus.
Aspiration biopsy
lAspiration biopsy is the use of a needle and syringe to penetrate a lesion for aspiration if its contents.
lIndications:
–To determine the presents of fluid within a lesion
–To a certain the type of fluid within a lesion
–When exploration of an intraosseous lesion is indicated
incisional biopsy
lAn incisional biopsy is a biopsy that samples only a particular portion or representative part of a lesion.
lIf a lesion is large or has different characteristics in various locations more than one area (extensive lesions) may need to be sampled.
Indication:
–Size limitations
–Hazardous location of the lesion
–Great suspicion of malignancy
Excision biopsy
An excisional biposy implies the complete removal of the lesion.
lIndications:
–Should be employed with small lesions. ( Less than 1cm )
–The lesion on clinical exam appears benign.
–When complete excision with a margin of normal tissue is possible without mutilation.
Dangers of Biopsy:
- spreading of tumors cells
- infection
- hemorrhage
- faliure of tissue to heal
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